Clinical Practice Guidelines

What are clinical practice guidelines (CPG)?

Clinical Practice Guidelines We Can Trust – Institute of Medicine (USA)


Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. 

CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes.

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National. Institute for Health and Care Excellence (NICE)

The National Institute for Health and Care Excellence (NICE) provides national guidance and advice to improve health and social care in England.

Our guidance, advice, quality standards and information services for health, public health and social care. Also contains resources to help maximise use of evidence and guidance.

Essential information for key groups including GPs, local government, public health professionals and members of the public. 



A WHO guideline is any document containing recommendations about health interventions, whether these are clinical, public health or policy recommendations. A recommendation provides information about what policy-makers, health-care providers or patients should do. It implies a choice between different interventions that have an impact on health and that have implications for the use of resources. Guidelines are recommendations intended to assist providers and recipients of health care and other stakeholders to make informed decisions. WHO has adopted internationally recognized standards and methods for guideline development to ensure that guidelines are free from bias, meet a public health need and are consistent with the following principles.

■ Recommendations are based on a comprehensive and objective assessment of the available evidence.

■ The process used to develop the recommendations is clear. That is, the reader will be able to see how a recommendation has been developed, by whom, and on what basis

What are clinical practice guidelines (CPG)


Process of  designing and publishing CPG


Suggested methods of the CPG for Primary Care Physicians SL

CPG producers 

World Health Organization

NICE pathways